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Gas6 molecular weight

WebMar 23, 2024 · Since growth arrest-specific gene 6 (Gas6) was discovered in 1988, numerous studies have highlighted the role of the Gas6 protein and its receptors Tyro3, Axl and Mer (collectively referred to as TAM), in proliferation, apoptosis, efferocytosis, leukocyte migration, sequestration and platelet aggreg … WebAnti-GAS 6 antibody (ab136249) Datasheet SDS Reviews ( 3) Submit a question References (4) Key features and details Rabbit polyclonal to GAS 6 Suitable for: WB Reacts with: Human Isotype: IgG You may also be …

GAS6 antibody Immunohistochemistry, Western SAB4501121 GAS-6

WebDec 1, 2024 · Finally, Axl and Gas6 are a key molecular system exploited by flaviviruses, such as Ebola (EBV) or Zika (ZIKV) viruses 12, 13. The Axl/Gas6 system is also involved … WebMar 23, 2024 · Gas6 binds receptor tyrosine kinases (RTKs) of the TAM family, which comprises Tyro3, Axl and Mer, and then activates … briggs and stratton surging governor https://itsbobago.com

Analysis of Gas6 in Human Platelets and Plasma

WebFeb 3, 2024 · Here, we tested the hypothesis that expression of growth arrest–specific 6 (GAS6), the ligand of receptor tyrosine kinase AXL, is associated with chemotherapy response and that sequestration of GAS6 with AVB-S6–500 (AVB-500) could improve tumor response to chemotherapy and PARP inhibitors. WebSep 15, 2024 · Axl binds to a high affinity ligand growth arrest specific 6 (Gas6) that belongs to the vitamin K-dependent family of proteins. The Gas6/Axl signaling pathway has been implicated to promote progression, metastasis, immune evasion, and therapeutic resistance in many cancer types. WebMar 9, 2024 · These findings suggested that low expression of GAS6-AS1 might exert an essential role in AFST through downregulating its downstream target mRNAs GOLGA8A and BACH2, and GAS6-AS1 might be a potential target for AFST therapy. can you buy a stock and sell it the next day

GAS6 Protein Overview: Sequence, Structure, Function and Protein ...

Category:Recombinant Human GAS 6 protein (ab131810) Abcam

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Gas6 molecular weight

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WebJul 1, 2024 · GAS6 (growth arrest–specific gene-6) promotes PAR1 (protease-activated receptor-1)–dependent thrombin signaling to induce CCL2 (CC-chemokine ligand 2) expression in the flow-restricted inferior … Web康朗生物为您提供硫胺素酶thtpa抗体的参数及2024年最新报价,厂家专业的硫胺素酶thtpa抗体售后服务团队,是您值得信赖的 ...

Gas6 molecular weight

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WebGas6 is present at around 0.2 nM (18 ng mL−1) in normal human serum or plasma [4], whereas the anticoagulant protein S is present at a thousand-fold higher concentration … WebThe gene, designated gas6 by the authors, is expressed as an abundant 2.6-kb mRNA in starved cells but decreases significantly upon stimulation of cells with serum or fibroblast …

WebFeb 20, 2012 · While the majority of Mer from control samples existed as a 180-kDa band, Gas6-treated cells predominantly expressed a form of Mer with a faster electrophoretic mobility and approximate molecular weight of 150 kDa. WebAug 20, 2012 · GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling …

WebMar 23, 2024 · Gas6 is a 75 kDa secreted protein with a Gla domain at the N terminus that, based on its structure, belongs to the VKD protein family. 10 The Gla domain is generated by VKD γ -carboxylation of a... WebGas6 contains 678 amino acids, which may be divided into five domains (Fig. 1A). The Gla domain is rich in γ-carboxyglutamic acid (Gla) residues. The corresponding Gla domain …

WebJun 18, 2024 · Although the molecular weight of the full-length Axl is 104 kDa, post-translational modifications of the extracellular domains give rise to two modified forms with molecular weights 120 and 140 kDa. Potential N-linked glycosylation sites include Asn 43, Asn 157, Asn 198, Asn 339, Asn 345, and Asn 401 [ 15 ]. Figure 1.

Web1. Mass from volume & concentration Concentration: Formula Weight (daltons): Volume: Mass = 2. Volume from mass & concentration Mass: Formula Weight (daltons): Concentration: 3. Molarity from mass & volume Mass: Formula Weight (daltons): Volume: Molarity = 4. Dilute a stock solution Stock concentration: Desired concentration: Desired … briggs and stratton symphony iiWebTaken together, our results identified GAS6-AS1 as a noveltumorsuppressorinLUAD andunraveleditsunderlying molecular mechanism in reprogramming glucose metabolism. GAS6-AS1 potentially may serve as a prognostic marker and therapeutic target in LUAD. INTRODUCTION can you buy a starbucks gift card onlineWebJan 18, 2024 · Published 18 Jan 2024 Growth arrest-specific 6 (Gas6) is a gene cloned in 1993 [ 1] encoding for a vitamin K-dependent protein expressed in different tissues [ 1 – 3 ]. Its biological activities are mediated by the interaction with three tyrosine kinase receptors: Tyro3, Axl, and MerTK, which are commonly and collectively abbreviated as TAM [ 4 ]. can you buy a stock on the ex dividend date