Webcisplatin anticancer activity specifically in KRAS/LKB1 co-mutated patient-derived xenografts. Moreover, metformin prevented the development of acquired tumor resistance to 5 consecutive cycles of cisplatin treatment (75% response rate with metformin-cisplatin as compared to 0% response rate with cisplatin), while reducing CD133þ cells. Web1 apr. 2024 · Ou X, Zhou X, Shi Q, Xing X, Yang Y, Xu T, Shen C, Wang X, He X, Kong L, Ying H, Hu C. Treatment outcomes and late toxicities of 869 patients with nasopharyngeal carcinoma treated with definitive intensity modulated radiation therapy: new insight into the value of total dose of cisplatin and radiation boost. Oncotarget. 2015 Nov …
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Web21 nov. 2024 · Taken together, our observations suggest that metformin inhibits the inflammatory pathway induced by paclitaxel and cisplatin treatment. Furthermore, metformin in combination with paclitaxel or cisplatin improved the sensitivity in drug-resistant ovarian cancer cells. Web15 aug. 2024 · Metformin, cisplatin, cisplatin nano-cubosomes and cisplatin-metformin nano-cubosomes showed an increase of 2.5, 1.7, 2.15 and 3.6 fold after 24 h of treatment compared to the control. A marked elevation in the AMP/ATP ratio was detected after 48 … order whole cooked turkey
Metformin overcomes resistance to cisplatin in triple-negative breast c…
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